https://w3id.org/salon#SALON - Sequence ALingment Ontology for pairwise and multiple sequence alignments
| URI | https://w3id.org/salon#Alignment |
|---|---|
| Description |
Set of biological sequences, used to identify regions of similarity that may indicate functional, structural and/or evolutionary relationships between them. |
| Restrictions |
Has Alignment Scoreop some Alignment Scorec Has Subalignmentop some Sub Alignmentc Has Columnop some Alignment Columnc |
| Sub-classes |
Correct Alignmentc Incorrect Alignmentc |
| In domain of |
Has Columnop Has Subalignmentop Has Alignment Scoreop |
| In range of |
Is Column Ofop Is Subalignment Ofop |
| URI | https://w3id.org/salon#AlignmentColumn |
|---|---|
| Description |
A representation of a column in the alignment. Note that a column with all gaps is not allowed. |
| Restrictions |
Has Column Scoreop some Column Scorec |
| Sub-classes |
Unconfidently Aligned Columnc Confidently Aligned Columnc |
| In domain of |
Is Column Ofop Column weightdp Sequence indexdp Columndp Has Column Scoreop Consensus characterdp |
| In range of |
Has Columnop |
| URI | https://w3id.org/salon#AlignmentScore |
|---|---|
| Description |
A score given to the alignment. |
| Restrictions |
Has Column Score Functionop exactly 1 Alignment Score Functionc |
| In domain of |
Has Alignment Score Functionop |
| In range of |
Has Alignment Scoreop |
| URI | https://w3id.org/salon#AlignmentScoreFunction |
|---|---|
| Description |
The method used to calculate the scoring function. |
| Sub-classes |
Maximization Alignment Score Functionc Minimization Alignment Score Functionc |
| In range of |
Has Alignment Score Functionop |
| URI | https://w3id.org/salon#AlignmentSequence |
|---|---|
| Description |
An ordered succession of residues and gap characters in a sequence. For proteins, this is known as the primary structure. |
| Restrictions |
Has Featureop some Featurec |
| Sub-classes |
Protein Sequencec DNA Sequencec |
| In domain of |
Sequence Identifierdp Sequence lengthdp Has Featureop Sequencedp Sequence organismdp Is Sequence Ofop |
| In range of |
Has Sequenceop Is Feature Ofop |
| URI | https://w3id.org/salon#ColumnScore |
|---|---|
| Description |
A score given to a single column. |
| Restrictions |
Has Column Score Functionop exactly 1 Column Score Functionc |
| In domain of |
Has Column Score Functionop |
| In range of |
Has Column Scoreop |
| URI | https://w3id.org/salon#ColumnScoreFunction |
|---|---|
| Description |
The method used to calculate the scoring function for a given column. |
| Sub-classes |
Maximization Column Score Functionc Minimization Column Score Functionc Reliability Measurec |
| In range of |
Has Column Score Functionop |
| URI | https://w3id.org/salon#ConfidentlyAlignedColumn |
|---|---|
| Description |
Column in the alignment with high confidence score. |
| Super-classes |
Alignment Columnc |
| URI | https://w3id.org/salon#ConstructionMethod |
|---|---|
| Description |
The method or algorithm used to construct the sequence alignment. |
| Sub-classes |
Deterministic Approachc Stochastic Approachc |
| In range of |
Has Construction Methodop |
| Members |
DynamicProgramming |
| URI | https://w3id.org/salon#CorrectAlignment |
|---|---|
| Description |
Valid alignment in terms of scoring. |
| Super-classes |
Alignmentc |
| URI | https://w3id.org/salon#DNAAlignmentSequence |
|---|---|
| Description |
Nucleotides Sequence. |
| Super-classes |
Alignment Sequencec |
| URI | https://w3id.org/salon#DeterministicApproach |
|---|---|
| Description |
Approach that produces the same alignment every time. |
| Super-classes |
Construction Methodc |
| Sub-classes |
Iterative methodc Progressive methodc Hidden Markov modelc |
| URI | https://w3id.org/salon#EvolutionaryAlgorithm |
|---|---|
| Description |
Population-based optimization algorithm. |
| Super-classes |
Stochastic Approachc |
| Sub-classes |
Genetic Algorithmc |
| URI | https://w3id.org/salon#Feature |
|---|---|
| Description |
Structural or functional feature associated with a sequence, e.g., a region of interest, a secondary structure element, etc. |
| In domain of |
Feature notedp Feature typedp Is Feature Ofop Feature startdp Feature scoredp Feature stopdp |
| In range of |
Has Featureop |
| URI | https://w3id.org/salon#Genetic_Algorithm |
|---|---|
| Description |
Evolutionary computation technique inspired by biological evolution. |
| Super-classes |
Evolutionary algorithmc |
| URI | https://w3id.org/salon#HiddenMarkovModel |
|---|---|
| Description |
Probabilistic model that encapsulate the evolutionary changes of an alignment. |
| Super-classes |
Deterministic Approachc |
| Members |
MUMMALS |
| URI | https://w3id.org/salon#IncorrectAlignment |
|---|---|
| Description |
Invalid alignment in terms of scoring. |
| Super-classes |
Alignmentc |
| URI | https://w3id.org/salon#IterativeMethod |
|---|---|
| Description |
Heuristic that realigns the sequences during multiple iterations of the alignment process. |
| Super-classes |
Deterministic Approachc |
| Members |
MUSLCLE PRIME MAFFT |
| URI | https://w3id.org/salon#MaximizationAlignmentScoreFunction |
|---|---|
| Description |
The cost function to maximize (direction of optimization). |
| Super-classes |
Alignment Score Functionc |
| Members |
AlignmentScoreTC AlignmentScoreGUIDANCE |
| URI | https://w3id.org/salon#MaximizationColumnScoreFunction |
|---|---|
| Description |
The cost function to maximize (direction of optimization). |
| Super-classes |
Column Score Functionc |
| Members |
ColumnScoreNongapsPercentage ColumnScoreSOP ColumnScoreTC ColumnScoreGUIDANCE |
| URI | https://w3id.org/salon#MinimizationAlignmentScoreFunction |
|---|---|
| Description |
The cost function to minimize (direction of optimization). |
| Super-classes |
Alignment Score Functionc |
| URI | https://w3id.org/salon#MinimizationColumnScoreFunction |
|---|---|
| Description |
The cost function to minimize (direction of optimization). |
| Super-classes |
Column Score Functionc |
| Members |
ColumnScoreShannonEntropy |
| URI | https://w3id.org/salon#ProgressiveMethod |
|---|---|
| Description |
The alignment starts with one sequence and progressively aligns the others. |
| Super-classes |
Deterministic Approachc |
| Members |
ClustalW SATCHMO KAlign T-Coffee |
| URI | https://w3id.org/salon#Protein |
|---|---|
| Description |
The protein associated to an amino acid sequence. |
| In domain of |
Protein genedp Protein descriptiondp Protein namedp |
| In range of |
Has Association Withop |
| URI | https://w3id.org/salon#ProteinAlignmentSequence |
|---|---|
| Description |
Amino Acids Sequence. |
| Super-classes |
Alignment Sequencec |
| Restrictions |
Has Association Withop some Proteinc |
| In domain of |
Has Association Withop |
| URI | https://w3id.org/salon#ReliabilityMeasure |
|---|---|
| Description |
Reliability measure to estimate alignment accuracy. |
| Super-classes |
Column Score Functionc |
| In domain of |
Score Cutoffdp |
| Members |
ColumnScoreGUIDANCE |
| URI | https://w3id.org/salon#StochasticApproach |
|---|---|
| Description |
Approach that uses randomness to find an alignment. |
| Super-classes |
Construction Methodc |
| Sub-classes |
Evolutionary algorithmc |
| URI | https://w3id.org/salon#SubAlignment |
|---|---|
| Description |
A subset of sequences in the alignment. |
| Restrictions |
Has Sequenceop min 2 Alignment Sequencec |
| In domain of |
SubAlignment namedp Has Sequenceop Gap characterdp Has Construction Methodop Is Subalignment Ofop |
| In range of |
Is Sequence Ofop Has Subalignmentop |
| URI | https://w3id.org/salon#UnconfidentlyAlignedColumn |
|---|---|
| Description |
Column in the alignment with low confidence score. |
| Super-classes |
Alignment Columnc |
| URI | https://w3id.org/salon#associatedTo |
|---|---|
| Domain(s) | Protein Sequencec |
| Range(s) | Proteinc |
| URI | https://w3id.org/salon#constructionMethod |
|---|---|
| Domain(s) | Sub Alignmentc |
| Range(s) | ConstructionMethodc |
| URI | https://w3id.org/salon#hasAlignmentScore |
|---|---|
| Domain(s) | Alignmentc |
| Range(s) | AlignmentScorec |
| URI | https://w3id.org/salon#hasAlignmentScoreFunction |
|---|---|
| Domain(s) | Alignment Scorec |
| Range(s) | AlignmentScoreFunctionc |
| URI | https://w3id.org/salon#hasColumn |
|---|---|
| Inverse properties | Is Column Ofop |
| Domain(s) | Alignmentc |
| Range(s) | AlignmentColumnc |
| URI | https://w3id.org/salon#hasColumnScore |
|---|---|
| Domain(s) | Alignment Columnc |
| Range(s) | ColumnScorec |
| URI | https://w3id.org/salon#hasColumnScoreFunction |
|---|---|
| Domain(s) | Column Scorec |
| Range(s) | ColumnScoreFunctionc |
| URI | https://w3id.org/salon#hasFeature |
|---|---|
| Inverse properties | Is Feature Ofop |
| Domain(s) | Alignment Sequencec |
| Range(s) | Featurec |
| URI | https://w3id.org/salon#hasSequence |
|---|---|
| Inverse properties | Is Sequence Ofop |
| Domain(s) | Sub Alignmentc |
| Range(s) | AlignmentSequencec |
| URI | https://w3id.org/salon#hasSubalignment |
|---|---|
| Inverse properties | Is Subalignment Ofop |
| Domain(s) | Alignmentc |
| Range(s) | SubAlignmentc |
| URI | https://w3id.org/salon#isColumnOf |
|---|---|
| Domain(s) | Alignment Columnc |
| Range(s) | Alignmentc |
| URI | https://w3id.org/salon#isFeatureOf |
|---|---|
| Domain(s) | Featurec |
| Range(s) | AlignmentSequencec |
| URI | https://w3id.org/salon#isSequenceOf |
|---|---|
| Domain(s) | Alignment Sequencec |
| Range(s) | SubAlignmentc |
| URI | https://w3id.org/salon#isSubalignmentOf |
|---|---|
| Domain(s) | Sub Alignmentc |
| Range(s) | Alignmentc |
| URI | http://purl.uniprot.org/core/Recommended_Name |
|---|---|
| Equivalent properties | Protein namedp |
| URI | http://purl.uniprot.org/core/mnemonic |
|---|---|
| Equivalent properties | Accession numberdp |
| URI | https://w3id.org/salon#FNote |
|---|---|
| Domain(s) | Featurec |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#FScore |
|---|---|
| Domain(s) | Featurec |
| Range(s) | http://www.w3.org/2001/XMLSchema#float http://www.w3.org/2001/XMLSchema#integer |
| URI | https://w3id.org/salon#FStart |
|---|---|
| Description |
The start position of the feature. |
| Domain(s) | Featurec |
| Range(s) | xsd:intc |
| URI | https://w3id.org/salon#FStop |
|---|---|
| Description |
The end position of the feature. |
| Domain(s) | Featurec |
| Range(s) | xsd:intc |
| URI | https://w3id.org/salon#FType |
|---|---|
| Domain(s) | Featurec |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#accessionNumber |
|---|---|
| Description |
A unique identifier in the databases. Accession numbers should remain static between database updates. |
| Domain(s) | (Alignment Sequencec or Proteinc) |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#atSequenceIndex |
|---|---|
| Description |
The position of the column in the alignment. |
| Domain(s) | Alignment Columnc |
| Range(s) | xsd:integerc |
| URI | https://w3id.org/salon#column |
|---|---|
| Description |
Alignment column data (one character for each sequence). |
| Domain(s) | Alignment Columnc |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#columnWeight |
|---|---|
| Description |
A weight associated with a given column. |
| Domain(s) | Alignment Columnc |
| Range(s) | xsd:integerc |
| URI | https://w3id.org/salon#consensusCharacter |
|---|---|
| Description |
A consensus character that summarises the residue information contained in an alignment column. |
| Domain(s) | Alignment Columnc |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#description |
|---|---|
| Description |
A general description of the entity. |
| Domain(s) | (Alignment Sequencec or Proteinc) |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#gapCharacter |
|---|---|
| Description |
The character used to represent an insertion/deletion. |
| Super-properties | owl:topDataProperty |
| Domain(s) | Sub Alignmentc |
| Range(s) | http://www.w3.org/2001/XMLSchema#short http://www.w3.org/2001/XMLSchema#string |
| URI | https://w3id.org/salon#geneName |
|---|---|
| Description |
The gene by which the protein is encoded. |
| Domain(s) | Proteinc |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#identifier |
|---|---|
| Description |
The name or UID given to the sequence. |
| Domain(s) | Alignment Sequencec |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#keyword |
|---|---|
| Description |
A keyword provides information that can be used to generate indexes of the entries based on functional, structural, or other categories. |
| Domain(s) | (Alignment Sequencec or Proteinc) |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#length |
|---|---|
| Description |
The length of the sequence. |
| Domain(s) | Alignment Sequencec |
| Range(s) | xsd:intc |
| URI | https://w3id.org/salon#organism |
|---|---|
| Description |
The unique identifier of the organism that was the source of the sequence by the NCBI. |
| Domain(s) | Alignment Sequencec |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#proteinDescription |
|---|---|
| Domain(s) | Proteinc |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#proteinName |
|---|---|
| Description |
Recommended name of the protein associated to the amino acid sequence. |
| Domain(s) | Proteinc |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#score |
|---|---|
| Description |
A score or metric computed for the alignment. |
| Domain(s) | (Alignment Scorec or Column Scorec) |
| Range(s) | http://www.w3.org/2001/XMLSchema#float http://www.w3.org/2001/XMLSchema#integer |
| URI | https://w3id.org/salon#scoreCutoff |
|---|---|
| Description |
Cutoff value is used as a classification criterion to separate columns into reliable and unreliable based on the score value. |
| Domain(s) | Reliability Measurec |
| URI | https://w3id.org/salon#scoreMax |
|---|---|
| Domain(s) | (Alignment Score Functionc or Column Score Functionc) |
| Range(s) | http://www.w3.org/2001/XMLSchema#float http://www.w3.org/2001/XMLSchema#integer |
| URI | https://w3id.org/salon#scoreMin |
|---|---|
| Domain(s) | (Alignment Score Functionc or Column Score Functionc) |
| Range(s) | http://www.w3.org/2001/XMLSchema#float http://www.w3.org/2001/XMLSchema#integer |
| URI | https://w3id.org/salon#sequence |
|---|---|
| Description |
The sequence itself, made up of residues and gap characters. |
| Domain(s) | Alignment Sequencec |
| Range(s) | xsd:stringc |
| URI | https://w3id.org/salon#subAlignmentName |
|---|---|
| Domain(s) | Sub Alignmentc |
| Range(s) | xsd:stringc |
| URI |
https://w3id.org/salon#AlignmentScoreGUIDANCE
|
|---|
| URI |
https://w3id.org/salon#AlignmentScoreTC
|
|---|
| URI |
https://w3id.org/salon#ClustalW
|
|---|
| URI |
https://w3id.org/salon#ColumnScoreGUIDANCE
|
|---|
| URI |
https://w3id.org/salon#ColumnScoreNongapsPercentage
|
|---|
| URI |
https://w3id.org/salon#ColumnScoreSOP
|
|---|
| URI |
https://w3id.org/salon#ColumnScoreShannonEntropy
|
|---|---|
| Description | H ranges from 0 (only one residue in present at that position) to 4.322 (all 20 residues are equally represented in that position). Typically, positions with H >2.0 are considerered variable, whereas those with H < 2 are consider conserved. Highly conserved positions are those with H <1.0 (Litwin and Jores, 1992). A minimum number of sequences is however required (~100) for H to describe the diversity of a protein family. |
| URI |
https://w3id.org/salon#ColumnScoreTC
|
|---|
| URI |
https://w3id.org/salon#DynamicProgramming
|
|---|
| URI |
https://w3id.org/salon#KAlign
|
|---|
| URI |
https://w3id.org/salon#MAFFT
|
|---|
| URI |
https://w3id.org/salon#MUMMALS
|
|---|
| URI |
https://w3id.org/salon#MUSLCLE
|
|---|
| URI |
https://w3id.org/salon#PRIME
|
|---|
| URI |
https://w3id.org/salon#SATCHMO
|
|---|
| URI |
https://w3id.org/salon#T-Coffee
|
|---|
https://w3id.org/salon#https://brickschema.org/schema/Brick#http://www.w3.org/ns/csvw#http://purl.org/dc/elements/1.1/http://purl.org/dc/dcam/http://www.w3.org/ns/dcat#http://purl.org/dc/dcmitype/http://purl.org/dc/terms/http://usefulinc.com/ns/doap#http://xmlns.com/foaf/0.1/https://w3id.org/obda/vocabulary#http://www.w3.org/ns/odrl/2/http://www.w3.org/ns/org#http://www.w3.org/2002/07/owl#http://www.w3.org/ns/dx/prof/http://www.w3.org/ns/prov#http://purl.org/linked-data/cube#http://www.w3.org/1999/02/22-rdf-syntax-ns#http://www.w3.org/2000/01/rdf-schema#https://schema.org/http://www.w3.org/ns/shacl#http://www.w3.org/2004/02/skos/core#http://www.w3.org/ns/sosa/http://www.w3.org/ns/ssn/http://www.w3.org/2003/11/swrl#http://swrl.stanford.edu/ontologies/3.3/swrla.owl#http://www.w3.org/2003/11/swrlb#http://www.w3.org/2006/time#http://purl.uniprot.org/core/http://purl.org/vocab/vann/http://rdfs.org/ns/void#http://www.w3.org/2001/XMLSchema#| c | Classes |
| op | Object Properties |
| fp | Functional Properties |
| dp | Data Properties |
| ap | Annotation Properties |
| p | Properties |
| ni | Named Individuals |